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ONCOLOGY, NUCLEAR MEDICINE AND TRANSPLANTOLOGY
Original Article
Jun 05, 2026 5 2

Histological Findings of Patients with Locally Advanced Colorectal Cancer After En Bloc Resection of the Urinary Bladder, Ureter or Prostate

Anuar Zhanapiya 1 * ,
Meiram Mamlin 1 2 *
1 School of Medicine, Nazarbayev University, Astana, Kazakhstan2 Department of Multidisciplinary Surgery, National Research Oncology Center, Astana, Kazakhstan* Corresponding Author
Oncology, Nuclear Medicine and Transplantology, 2(2), 2026, onmt019, https://doi.org/10.63946/onmt/18720
Publication date: Jun 05, 2026
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ABSTRACT

This study was conducted to investigate histological outcomes of patients with locally advanced colorectal cancer involving the urinary bladder, ureters or prostate. Initial cohort included 45 patients but 10 patients were eliminated from the study due to absence of medical records or non-confirmed colon adenocarcinoma. Finally, the study included 35 patients who underwent colon surgery plus either partial or complete bladder resection, partial ureter resection or prostate resection in time period between 2016 and 2025. Data on patient characteristics and results of histological examination were collected retrospectively. Among patients, who underwent colon surgery plus cystectomy (n=27), only in 48% cases confirmed histological invasion was detected. Overall R0 resection was achieved in 94% cases. These data correspond to literature reviewed findings. True lower urinary tract invasion occurred in approximately half of locally advanced colorectal cancer cases, while en bloc resection achieved high R0 rates, supporting resection when invasion is uncertain.

KEYWORDS

Locally Advanced Colorectal Cancer Bladder Invasion Ureter Invasion Cystectomy Multivisceral Resection

CITATION (Vancouver)

Zhanapiya A, Mamlin M. Histological Findings of Patients with Locally Advanced Colorectal Cancer After En Bloc Resection of the Urinary Bladder, Ureter or Prostate. Oncology, Nuclear Medicine and Transplantology. 2026;2(2):onmt019. https://doi.org/10.63946/onmt/18720
APA
Zhanapiya, A., & Mamlin, M. (2026). Histological Findings of Patients with Locally Advanced Colorectal Cancer After En Bloc Resection of the Urinary Bladder, Ureter or Prostate. Oncology, Nuclear Medicine and Transplantology, 2(2), onmt019. https://doi.org/10.63946/onmt/18720
Harvard
Zhanapiya, A., and Mamlin, M. (2026). Histological Findings of Patients with Locally Advanced Colorectal Cancer After En Bloc Resection of the Urinary Bladder, Ureter or Prostate. Oncology, Nuclear Medicine and Transplantology, 2(2), onmt019. https://doi.org/10.63946/onmt/18720
AMA
Zhanapiya A, Mamlin M. Histological Findings of Patients with Locally Advanced Colorectal Cancer After En Bloc Resection of the Urinary Bladder, Ureter or Prostate. Oncology, Nuclear Medicine and Transplantology. 2026;2(2), onmt019. https://doi.org/10.63946/onmt/18720
Chicago
Zhanapiya, Anuar, and Meiram Mamlin. "Histological Findings of Patients with Locally Advanced Colorectal Cancer After En Bloc Resection of the Urinary Bladder, Ureter or Prostate". Oncology, Nuclear Medicine and Transplantology 2026 2 no. 2 (2026): onmt019. https://doi.org/10.63946/onmt/18720
MLA
Zhanapiya, Anuar et al. "Histological Findings of Patients with Locally Advanced Colorectal Cancer After En Bloc Resection of the Urinary Bladder, Ureter or Prostate". Oncology, Nuclear Medicine and Transplantology, vol. 2, no. 2, 2026, onmt019. https://doi.org/10.63946/onmt/18720

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