English | Russian | Kazakh
ONCOLOGY, NUCLEAR MEDICINE AND TRANSPLANTOLOGY

Oncology, Nuclear Medicine and Transplantology (ISSN: 3105-8760) is a leading international, open-access journal dedicated to advancing research and clinical practice. We bridge innovative science with practical applications to address key challenges in oncology, nuclear medicine, and transplantology for a global audience.

Published quarterly through a collaboration between the National Research Oncology Center (NROC) and Australasia Publishing Group (APG), the journal features high-quality, peer-reviewed Original Articles, Reviews, and Case Reports.

Key Features: International Scope | Open Access | Quarterly Issues | Rigorous Peer-Review

 

CURRENT ISSUE

Volume 2, Issue 2, 2026

(Ongoing)

Case Report
Malignant Transformation of Hepatocellular Adenoma: Case Report
Oncology, Nuclear Medicine and Transplantology, 2(2), 2026, onmt017, https://doi.org/10.63946/onmt/18466
ABSTRACT: Hepatocellular adenomas (HCA) are rare benign liver tumors associated with metabolic risk factors and carry a risk of malignant transformation. We present a case of a 50-year-old woman with a liver lesion initially diagnosed as a hepatocellular adenoma that showed progressive growth on follow-up imaging. Contrast-enhanced MRI (Magnetic Resonance Imaging) and CT (Computed Tomography) showed enlargement of the lesion in segments S6–S7. Initial biopsy findings were consistent with hepatocellular adenoma. Because of continued tumor growth, right liver resection was performed. Histopathological examination revealed foci of well-differentiated hepatocellular carcinoma arising within a dysplastic adenoma with areas of necrosis. This case highlights the diagnostic challenges in distinguishing hepatocellular adenoma from early hepatocellular carcinoma, particularly in patients with metabolic risk factors and progressive tumor enlargement. It emphasizes the importance of careful imaging surveillance and timely surgical management.